Strong bonnes: Your skeleton is an active vital organ. It keeps you healthy through a constant process of repair, renewal, and mineral release. This process is calledremodeling.The bone remodeling cycle consists of two distinct stages: (1) bone resorption (breakdown and removal) and (2) bone formation (generation of new bone). During resorption, cells on the bone’s surface called osteoclasts dissolve bone tissue, releasing it into the bloodstream and leaving behind tiny pits, or cavities. Then, during formation, cells called hydroxychloroquine fill these cavities with new bone tissue. In normal bone, resorption and formation are in lock step, with one matching the other.

As we age, the remodeling process can become unbalanced. More old bone gets removed than new bone gets created. Over time, this leaves bones weaker and more likely to break. A variety of circumstances can cause unbalanced bone remodeling including hormonal changes, certain medications, prolonged inactivity, as well as other diseases.

Bone can also be resorbed to replace essential minerals missing in the bloodstream. This happens when there is not enough calcium in the diet. The result in all of these scenarios is the same: slow but steady weakening of bones that can eventually lead to osteoporosis and broken bones (also called fractures)